I am really proud to share this work wrote by Post-Doc Dr. Gianluca Casotti, as corresponding author, that was recently published on the new journal "Organics". In our laboratory Sos & PePSy, and in our department of chemistry in Pisa, through fruitful collaborations, we try to enhance the value of good ideas and good will. Gianluca had a good idea, and with my collegue Prof. Anna Iuliano we believed on it. The method developed allowed the synthesis of chalcones through a path involving an acylative Negishi coupling. The key point of this strategy is the preparation of the organozinc by direct insertion which is reflected in a superior functional-group tolerance and an improved intrinsic greenness. Different functional groups as well as heteroaryl rings are well-tolerated.
